What is a peripheral nerve block (PNB)?
- Injection of local anaesthetic (LA) near a peripheral nerve or nerve bundle to reduce pain (and sometimes movement) in a specific body region.
- Goal: excellent analgesia with less opioid, earlier mobilisation, and better patient experience.
- Blocks can be single-shot (one injection) or continuous (catheter infusion).
- “Sensory block” = numbness/analgesia; “motor block” = weakness/paralysis; most blocks give some of both depending on site and LA dose.
- Regional anaesthesia is a team activity: patient selection, consent, monitoring, and rescue plans matter as much as needle placement.
Common blocks you will meet early (conceptual map)
- Upper limb: interscalene (shoulder), supraclavicular (arm), infraclavicular/axillary (forearm/hand).
- Lower limb: femoral or fascia iliaca (hip/anterior thigh), adductor canal (knee analgesia with less weakness), popliteal sciatic (below-knee/foot).
- Trunk: TAP block (abdominal wall), rectus sheath (midline abdominal wall), erector spinae plane (thoracic/abdominal analgesia).
- Rule of thumb: more proximal brachial plexus blocks cover more of the arm but can have more respiratory/nerve-related side effects.
- Many “plane blocks” (e.g., TAP, ESP) target nerves in tissue planes rather than a single named nerve.
Indications and benefits (when blocks help most)
- Surgery with significant postoperative pain (e.g., shoulder, rib fractures, major knee/foot surgery, abdominal wall incisions).
- Patients where opioid minimisation is helpful: obstructive sleep apnoea, frailty, nausea/vomiting history, opioid sensitivity.
- Day-case pathways: good analgesia can reduce unplanned admissions and improve mobilisation.
- Trauma: can facilitate positioning, imaging, splinting, and reduce distress (ensure neurovascular assessment is documented first).
Contraindications and cautions (intro level)
- Absolute: patient refusal; infection at injection site; true LA allergy (rare—often preservative-related).
- Relative: anticoagulation/coagulopathy (site-dependent bleeding risk—follow local/regional guidance); severe sepsis; inability to cooperate; raised compartment syndrome risk where pain is a key sign (discuss with seniors).
- Pre-existing neuropathy: not an absolute contraindication, but document baseline symptoms and counsel about uncertainty of postoperative nerve symptoms.
- Respiratory compromise: some upper limb blocks (especially interscalene) can affect breathing—seek senior input.
- Always consider whether the block will cause problematic weakness (e.g., femoral block and falls risk).
Consent and communication (what to cover simply)
- Explain purpose: “to reduce pain during and after surgery; you may still need other pain relief.”
- Set expectations: numbness and weakness are common; duration varies; protect the limb until sensation returns.
- Discuss common risks: bruising, failure/partial block, temporary nerve symptoms, infection, bleeding.
- Discuss serious but rare risks: local anaesthetic systemic toxicity (LAST), long-term nerve injury, pneumothorax (certain upper chest blocks).
- Confirm laterality and site with the patient and the surgical team; mark the correct side per local policy.
Safety essentials before you start (the ‘block checklist’ mindset)
- Correct patient, correct side, correct procedure; allergies checked; anticoagulation status reviewed.
- Baseline neuro exam documented (sensation/movement) and pain score recorded.
- IV access in place; standard monitoring (ECG, NIBP, SpO2) and oxygen available.
- Resuscitation equipment immediately available; intralipid (lipid emulsion) accessible for LAST.
- Time-out immediately before needle insertion: confirm block type, side, LA drug and dose, and plan for complications.
- Use aseptic technique: hand hygiene, sterile gloves, skin prep, sterile probe cover/gel if using ultrasound.
Local anaesthetic basics (practical, exam-relevant)
- Think in TOTAL dose (mg), not just volume: check concentration and calculate maximum safe dose for the patient.
- Use the lowest effective dose/volume, especially for high-risk sites or small patients.
- Incremental injection with frequent aspiration reduces intravascular injection risk (but does not eliminate it).
- Adrenaline-containing LA can reduce systemic absorption and acts as a marker of intravascular injection (tachycardia), but is not suitable for all patients.
- Additives (e.g., dexamethasone) may prolong analgesia—use only if within local policy and with senior agreement.
Ultrasound vs nerve stimulation (conceptual)
- Ultrasound helps identify anatomy, needle tip position, and spread of LA; it does not guarantee safety.
- Nerve stimulation can help confirm proximity to motor nerves; absence of twitch does not guarantee correct placement.
- Best practice often combines ultrasound guidance with careful technique: visualise needle tip, inject small test aliquots, watch spread, and stop if pain/paraesthesia occurs.
- Never inject against high resistance; stop and reassess needle position.
Block assessment and postoperative advice
- Assess sensory change in the expected distribution (cold/light touch) and motor function where relevant; document findings.
- If block is incomplete: consider time (some take 20–40 minutes), top-up options, or alternative analgesia—escalate early.
- Protect numb limbs: sling for upper limb; falls precautions for lower limb; avoid heat sources (burn risk).
- Give clear discharge advice for day-case patients: expected duration, when to start oral analgesia, and when to seek help.
Complications you must recognise early
- LAST: tinnitus, metallic taste, agitation, seizures, reduced consciousness, arrhythmias, cardiovascular collapse—treat as an emergency.
- Nerve injury: severe pain on injection, persistent numbness/weakness beyond expected duration, new neuropathic pain—stop injection and seek senior review.
- Bleeding/haematoma: increased risk with anticoagulants; swelling, pain, neurological changes—urgent assessment.
- Infection: rare with single-shot; higher with catheters—monitor for redness, fever, discharge.
- Site-specific: pneumothorax risk with some upper chest blocks; diaphragmatic weakness with interscalene; falls with femoral-type blocks.
What is the main reason we do peripheral nerve blocks?
– Better pain relief in a targeted area – Less opioid (less nausea, sedation, respiratory depression) – Often faster mobilisation and discharge
What are the absolute contraindications to a nerve block?
– Patient refusal – Infection at the injection site – True local anaesthetic allergy (rare)
What monitoring do I need for a block?
– IV access – ECG, blood pressure, pulse oximetry – Oxygen available – Full resus equipment and lipid emulsion accessible
How do I reduce the risk of intravascular injection and LAST?
– Use ultrasound where appropriate – Aspirate frequently – Inject in small incremental doses with pauses – Use the lowest effective total dose – Stop immediately if symptoms occur
What should make me stop injecting immediately?
– Severe pain or paraesthesia on injection – High resistance to injection – Patient becomes unwell (tinnitus, metallic taste, agitation) – You cannot see/confirm needle tip position
How do I know if the block is working?
– Sensory change in the expected area (cold/light touch) – Motor weakness may occur depending on block – Allow time: some blocks take 20–40 minutes for full effect
What is a ‘plane block’ (e.g., TAP, ESP) in simple terms?
– LA is injected into a tissue plane where small nerves run – Often gives good analgesia for the body wall (skin/muscle) – Usually less dense motor block than plexus blocks
Why do some lower limb blocks increase falls risk?
– If the block affects motor nerves (e.g., quadriceps weakness), the leg may buckle – Use mobility precautions and consider motor-sparing options (e.g., adductor canal) when appropriate
What are the early signs of LAST I should look for?
– Ringing in ears, metallic taste, dizziness – Agitation/confusion – Seizure – Then cardiovascular instability/arrhythmias
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