When tiva is useful

What is TIVA (and why choose it)?

  • TIVA = maintaining general anaesthesia using intravenous drugs (commonly propofol + an opioid such as remifentanil), rather than inhaled volatile agents.
  • Often delivered using a target-controlled infusion (TCI): a pump that aims for a chosen drug concentration (e.g., effect-site target for propofol).
  • Main reasons to choose TIVA: reduce postoperative nausea/vomiting (PONV), avoid volatile-related issues, improve conditions for certain surgeries, and provide stable anaesthesia when gases are impractical.

High PONV risk (common and exam-relevant)

  • TIVA with propofol reduces PONV compared with volatile anaesthesia (useful in patients with previous severe PONV or multiple risk factors).
  • Particularly helpful for day-case surgery where early discharge matters.
  • Still use multimodal antiemetics as indicated (TIVA reduces risk but does not eliminate it).

Airway surgery and shared-airway cases

  • Useful when the surgeon needs access to the airway (e.g., microlaryngoscopy, bronchoscopy) and volatile delivery may be unreliable due to leaks or open circuits.
  • Maintains anaesthesia when ventilation is intermittent or via non-standard techniques (e.g., jet ventilation) where end-tidal agent monitoring is limited.
  • Plan depth monitoring carefully (clinical signs ± processed EEG if used locally) because you may not have end-tidal agent as a guide.

Neurosurgery and neuro-anaesthesia considerations

  • Propofol-based TIVA can help provide a “slack brain” (reduced cerebral blood flow and intracranial pressure) compared with some volatile techniques.
  • Useful when stable physiology and rapid wake-up for neurological assessment are desired.
  • Common in cases needing neurophysiological monitoring (e.g., motor evoked potentials), where volatile agents can suppress signals (local protocols vary).

When inhalational anaesthesia is undesirable or impractical

  • Malignant hyperthermia (MH) susceptibility: avoid triggering agents (volatile agents and suxamethonium); TIVA is a standard approach (ensure full MH precautions and machine preparation).
  • Severe bronchospasm/reactive airways: propofol and opioids may be better tolerated than pungent volatiles in some patients (individualise; ensure bronchodilator plan).
  • Poor access to anaesthetic machine or scavenging limitations (e.g., some remote locations): TIVA may be logistically simpler, but only if infusion equipment and monitoring are robust.

Procedures needing stillness or controlled conditions

  • Some ENT, ophthalmic, and interventional radiology procedures benefit from minimal movement and stable depth (remifentanil is useful for intense, short-lived stimulation).
  • Useful when you want predictable wake-up (e.g., short cases, rapid turnover), especially with remifentanil and careful propofol titration.
  • Can be advantageous where low fresh gas flows/volatile wash-in and wash-out would otherwise slow control of depth.

Practical tips for new starters (safe first-time use)

  • Always run a continuous opioid alongside propofol for surgical anaesthesia (propofol alone is not enough for most operations).
  • Use a dedicated IV cannula for infusions where possible; check patency before induction and re-check after positioning/draping.
  • Secure lines well and keep the cannula visible if feasible; extravasation or disconnection can cause awareness.
  • Have a clear plan for: induction, maintenance targets, analgesia, antiemetics, and emergence (including postoperative pain plan if using remifentanil).
  • If using neuromuscular blockade, ensure appropriate monitoring and reversal plan; paralysis can mask inadequate depth.
  • Document drug concentrations, pump settings/targets, and any changes with time stamps.
What does TIVA stand for and what is the usual drug combination?

Total intravenous anaesthesia. Commonly propofol (hypnotic) + an opioid infusion (often remifentanil; sometimes alfentanil/fentanyl) ± muscle relaxant as needed.

When is TIVA particularly useful for day-case patients?

– High PONV risk – Previous severe PONV – When early eating/drinking and discharge are priorities

Why can TIVA be useful in shared-airway surgery?

– Volatile delivery may be unreliable due to leaks/open airway – End-tidal agent monitoring may be limited – IV delivery maintains anaesthesia independent of the airway circuit

When should you strongly consider TIVA for MH risk?

Known or suspected MH susceptibility: avoid volatile agents and suxamethonium; use a non-trigger technique (often propofol-based TIVA) with full MH precautions and prepared equipment.

What is the main safety concern with TIVA compared with volatile anaesthesia?

– Accidental interruption of drug delivery (disconnection, occlusion, empty syringe, wrong line) – Risk of awareness if infusion stops, especially if paralysed

How do you reduce the risk of awareness with TIVA?

– Check IV access and secure lines – Use reliable pumps and correct drug concentrations – Regularly confirm infusion running and syringe volume – Consider depth monitoring where appropriate and follow local policy – Avoid long periods of paralysis without reassurance of adequate anaesthesia

Why can remifentanil be a double-edged sword?

– Great for intense, short stimulation and rapid wake-up – But it wears off quickly: you must plan longer-acting analgesia (e.g., morphine/oxycodone, regional block, paracetamol/NSAID if appropriate) before stopping it

Is propofol alone enough for surgical anaesthesia?

Usually no. Propofol provides hypnosis (sleep) but limited analgesia; most surgery needs an opioid and/or regional/local anaesthesia.

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